Has the federal government made recommendations to protect human health? Other glycol ethers, such as EGME/EGBE, are a group of compounds that are used as organic solvents in various products. 2-Butoxyethanol has long been known to be toxic, with early studies indicating that a single seven-hour exposure to 700 ppm was lethal to laboratory animals (Werner, Mitchell, Miller, and von Oettingen 1943a, as cited in ACGIH 1986/Ex. Those could include breathing problems, low blood pressure, lowered levels of hemoglobin, blood in the urine, and metabolic acidosis (high levels of acid in the body). It is advertised as an environmentally friendly, non-toxic, and biodegradable cleaner. Those could include breathing problems, low … In air, 2-butoxyethanol and 2-butoxyethanol acetate may 111-76-2) are rare despite the prevalence of this glycol ether in products such as glass and surface cleaners. D'après l'Inventaire national des rejets de polluants (INRP), la plupart des rejets déclarés dans l'environnement se font vers l'atmosphère, hormis quelques rejets dans l'eau. 2-Butoxyethanol and 2-butoxyethanol acetate do not build Hemolysis, a primary toxic effect associated with 2-butoxyethanol exposure in rodents, increased hemosiderin (iron) deposition in Kupffer cells … 2-Butoxyethanol (C ₄ H ₉ OCH ₂ CH ₂ OH) is a colorless liquid with a mild odor. For using cleaning products containing butoxyethanol in the home, follow safe handling instructions included on the label to minimize potential exposure. 2-Butoxyéthanol France (VLEP contraignante) 10 49 50 246 2-Butoxyéthanol Allemagne (valeurs MAK) 10 49 - - 2-Butoxyéthanol États-Unis (ACGIH) 20 97 - - Méthodes de détection et de détermination dans l'air Intermédiaire de synthèse organique, notamment pour la fabrication de l'acétate de 2-butoxyéthyle. 2-Butoxyethanol. 2-Butoxyethanol and 2-butoxyethanol acetate may be released The National Emission Standards for Hazardous Air Pollutants regulates 2-butoxyethanol under the Clean Air Act because it has demonstrated the potential to cause serious health issues including reduced fertility, low birth weight and toxic liver metabolites. Background: Severe toxic ingestions of butoxyethanol (CAS No. SCA endorses products with the Toxic-Free Tick, that do not contain butoxyethanol CAS 111-76-2. “2-Butoxyethanol is readily absorbed following inhalation, oral, and dermal exposure. It is a known respiratory irritant and can be acutely toxic but animal studies did not find it to be mutagenic, and no studies suggest it is a human … Though it can also be found in household cleaners. Butoxyethanol is also regulated under the Clean Air Act, including the National Emission Standards for Hazardous Air Pollutants. ATSDR can also tell you the location of occupational and environmental health clinics. Butoxyethanol is a solvent in spray lacquers, enamels, varnishes, and latex paints due to its ability to clean grease and dirt. 2-Butoxyethanol Petroleum Uses This product is an essential component of fracturing fluids, drilling stabilizers, and oil slick dispersants for water-based and oil-based hydraulic fracturing. products. Breathing in large amounts of 2-butoxyethanol or 2-butoxyethanol acetate may result in irritation of the nose and eyes, headache, and vomiting. Many people are exposed to small amounts of 2-butoxyethanol Exposures to butoxyethanol are more likely to occur in the workplace, for example in spray-painting operations or automobile repair shops, rather than in the environment or at home. To help protect workers who use butoxyethanol in occupational settings, the U.S. Occupational Safety and Health Administration (OSHA) has set an exposure limit of 50 parts of 2-butoxyethanol per million parts of air (50 ppm) for an 8-hour workday, 40-hour workweek. On importe le 2-butoxyéthanol pour utilisation comme ingrédient de formulations, de produits de consommation ou d'articles fabriqués, ainsi que comme adjuvant de traitements chimiques. It's used a a solvent in paint strippers, thinners. How likely is 2-butoxyethanol and 2-butoxyethanol acetate to cause cancer? When tested undiluted, 2-butoxyethanol is a severe eye irritant (CICAD 1998). For risk characterisation purposes therefore, haemotoxicity will be the end point chosen keeping in mind the interspecies differences (human/rodents) to calculate margin of safety. and automobile repair shops that use materials containing Butoxyethanol helps decrease the overall thickness of a varnish or paint to help enable smoother application. According to the U.S. Agency for Toxic Substances & Disease Registry (ATSDR), inappropriately or accidentally swallowing large amounts of cleaning agents containing butoxyethanol can cause harmful effects for people. Overview. It is imported for use mainly as a component of formulations, as part of consumer products or manufactured articles, and as a chemical processing aid. 2-Butoxietanol 2-Butoxyethanol has moderate acute toxicity and is irritating to the eyes and skin; it is not a skin sensitizer.” Butoxyethanol also can help keep a substance clear—even after a product is exposed to extreme temperatures during shipping or storage. You may have seen 2-Butoxyethanol as Ethylene Glycol Monobutyl Ether, Butyl Glycol, Butyl Oxitol, or Glycol Butyl Ether and more. and 2-butoxyethanol acetate every day. This toxic body burden is EWG’s chief concern about household chemicals. Maybe if you’re exposed to a chemical a handful of times it wouldn’t cause harm, but some chemicals build up enough or cause enough harm in your body over time that it triggers some kind of disease outcome. It received critical attention from environmental safety activists because of the toxicity concerns of 2-butoxyethanol (EGBE), which was in the formula at under 4%. The compound is classified as glycol ether, a group of powerful solvents that should not be toyed with. The level of exposure depends upon the dose, duration, and work being done. Some harmful effects of 2-butoxyethanol have been seen in animals such as rats and rabbits. 203-905-0. Living near a hazardous waste site where 2-butoxyethanol It is imported for use mainly as a component of formulations, as part of consumer products or manufactured articles, and as a chemical processing aid. Other reproductive effects and birth defects in animals have only been observed at doses that were toxic to the adult animals." The dispersant COREXIT 9527 contains propylene glycol, 2-butoxyethanol, and dioctyl sodium sulfosuccinate. 2-Butoxyethanol … These compounds enhance the dispersion of oil by reducing … Common household cleaning products like glass cleaners, liquid soaps and all-purpose spray-cleaners contain butoxyethanol, for its ability to help dissolve substances such as grease and dirt. Butoxyethanol is also regulated under the Clean Air Act, including the National Emission Standards for Hazardous Air Pollutants. What happens to 2-butoxyethanol and 2-butoxyethanol acetate when it enters the environment? *Please select more than one item to compare How might I be exposed to 2-butoxyethanol and 2-butoxyethanol acetate? recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. There are no data on whether butoxyethanol causes reproductive effects, birth defects, or cancer in people, according to ATSDR. What is 2-butoxyethanol and 2-butoxyethanol acetate? Eye irritation. The EPA has identified this chemical as especially hazardous when inhaled. You can normally find 2-Butoxyethanol in window and kitchen cleaners. Use the search box to find information on the chemicals that are essential to the products you use every day. According to the U.S. Agency for Toxic Substances & Disease Registry (ATSDR), inappropriately or accidentally swallowing large amounts of cleaning agents containing butoxyethanol can cause harmful effects for people. A colorless liquid with a sweet scent, butoxyethanol is primarily used in paints and coatings, and also is an ingredient some household cleaning products, cosmetics and personal care products. 2-Butoxyethanol. Butoxyethanol is also an ingredient in adhesives and inks used on food packaging. 2-Butoxyethanol has been found in at least 20 of the 1,430 National Priorities List sites … Is there a medical test to show whether I've been exposed to 2-butoxyethanol and 2-butoxyethanol acetate? 888-232-6348 (TTY) Use restrictions (moderate), Non-reproductive organ system toxicity (low), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high) fragrance ingredient, solvent, viscosity decreasing agent, masking, and viscosity controlling Butoxyethanol is an ether alcohol. No studies have been found that tested butoxyethanol for causing cancer in animals, according to ATSDR. As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. Read more: Understanding Risk and Hazard When it Comes to Chemicals, butoxyethanol is safe in hair and nail products, U.S. Agency for Toxic Substances & Disease Registry (ATSDR). 2-Butoxyethanol is not currently produced in Canada. From all the studies, no specific relevant toxic effects, other that haemotoxicity, can be identified that are clearly related to treatment with 2 -butoxyethanol. Search results for butoxyethanol at Sigma-Aldrich. 4 Skin Irrit. It is also a common ingredient in in liquid soaps and cosmetics, as well as industrial and household cleaning products. Because this product can work as a surfactant, it is able to … As with other cleaning products, keep household products containing 2-butoxyethaol out of the reach of children to avoid accidental ingestion. Working in occupations such as silk-screening, printing, As the Centers for Disease Control and Prevention notes, exposure to 2-Butoxyethanol can harm your eyes, skin, kidneys, and blood. 2-Butoxyethanol is a clear colorless liquid that smells like ether. In COREXIT 9500 the toxic 2-butoxyethanol was replaced with light petroleum distillate. These could include breathing problems, low blood pressure, lowered levels of hemoglobin, blood in the urine, and metabolic acidosis (high levels of acid in the body). These clinics specialize in A U.S. Environmental Protection Agency review finds 2-butoxyethanol is not toxic to reproduction or development. Don’t use Butyl Cellosolve. This chemical is known by many different names, which are a mouthful, to say the least. HP6 Acute Toxicity: waste which can cause acute toxic effects following oral or dermal administration, or inhalation exposure. 2010. low U.S. Environmental Protection Agency. Butoxyethanol was nephrotoxic in an intravenous study in rats, but not when administered intraperitoneally. 2-Butoxyethanol is a colorless liquid with a mild odor. Acute Tox. Both compounds may pass into air from water and soil. 2-Butoxyethanol increases hemangiosarcomas selectively in male mouse liver after chronic inhalation through mechanisms that have not fully been elucidated. Based on the National Pollutant Release Inventory (NPRI), most reported environmental releases are to the atmosphere, with some minor releases to water. Note: Javascript is disabled or is not supported by your browser. It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol, and butyl Oxitol. 2-Butoxyethanol is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2). The CIR Expert Panel reviewed the scientific data and concluded that Butoxyethanol is safe in hair and nail products at concentrations up to 10.0%. and 2-butoxyethanol acetate are disposed of. The safety of Butoxyethanol has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. No evidence of genotoxicity was seen in a battery of tests with metabolic activation, but positive and negative effects were seen in the absence of metabolic activation. Manifestations of acute butoxyethanol toxicity include metabolic acidosis, hemolysis, hepatorenal dysfunction, and coma, but vary widely in reported cases. 2-Butoxyethanol. 111-76-2. Workers may be harmed from exposure to 2-butoxyethanol. HP4 Irritant — skin irritation and eye damage: waste which on application can cause skin irritation or damage to the eye. Exposure to 2-butoxyethanol and butoxyethanol acetate occurs mainly from breathing air or having skin contact with household products containing them. furniture production and finishing, spray-painting operations, Butyl Cellosolve (CAS #111-76-2 also known as Butyl Cellusolve, Butoxyethanol, Butyl Glycol and Ethylene Glycol Monobutyl Ether) is a toxic agent used in many industrial and domestic cleaners – many of which claim to be non-hazardous.It is absorbed through the skin and lungs causing a variety of health issues depending on the level of exposure. Breathing air or having skin contact with household cleaners The Cosmetic Ingredient Review (CIR), an expert scientific panel sponsored by the Personal Care Products Council has assessed the safety of butoxyethanol in personal care products, concluding that butoxyethanol is safe in hair and nail products at concentrations at low levels (<10%) – per CIR’s recommendation. Sutton explains: “Our concern is daily, weekly, chronic exposure over a lifetime. This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol. Skin irritation. Compare Products: Select up to 4 products. Exposures near the lethal level caused systemic toxicity in the form of hemoglobinuria and lung, kidney, and liver changes. Butoxyethanol, also known as 2-Butoxyethanol, is a widely used solvent. or other liquids that contain these compounds. 2-Butoxyethanol - Identification, toxicity, use, water pollution potential, ... PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. How to avoid 2-Butoxyethanol Learn more about the chemistry in the products we rely on every day, including how and why particular chemicals are used in different products, and health and safety information about these chemicals. 1-3, p. 71). into the air when they are used as solvents and in household Diethylene glycol is used in numerous products including solvents and brake fluids. How can 2-butoxyethanol and 2-butoxyethanol acetate affect my health? 603-014-00-0. 2-Butoxyethanol and 2-butoxyethanol acetate may break This toxic chemical is mainly found in the kitchen, in glass and multi-purpose cleaners. Email: Contact CDC-INFO. When inhaled, 2-Butoxyethanol can cause sore a throat. For this reason, some items on this page will be unavailable. Print this Page. Toxic substances list: 2-butoxyethanol. Butoxyethanol was only slightly toxic in an acute oral study in rats and in a dermal study in rabbits. 2-Butoxyethanol was identified as a causal agent in the health problems experienced by cleanup workers after the 1989 Exxon Valdez oil spill. U.S. Agency for Toxic Substances & Disease Registry, U.S. Occupational Safety and Health Administration. down in air into other compounds within a few days. Chemsrc provides 2-butoxyethanol(CAS#:111-76-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. be removed by rain, ice, or snow. It can harm the eyes, skin, kidneys, and blood. This is the compound that gives many cleaners a sweet smell. Skin irritation and eye damage: waste which can cause acute toxic effects following oral or dermal administration or. [ 3 ] it is of low toxicity via the oral and dermal of! 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